imaging

Science & Nature Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling...

Science & Nature Two-dimensional strongly interacting electrons crystalize into a solid phase known as the Wigner crystal at low densities and form a Fermi...

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Science & Nature Researchers at the University of Arizona’s Wyant College of Optical Sciences have unveiled a groundbreaking 3D imaging technique to transform eye-tracking...

How can the latest technology, such as solar cells, be improved? An international research team led by the University of Göttingen is helping to find answers to questions like this with a new technique. For the first time, the formation of tiny, difficult-to-detect particles—known as dark excitons—can be tracked precisely in time and space...

Research Briefing Published: 31 March 2023 Nature Biotechnology (2023)Cite this article Subjects We present the Schmidt objective, a novel astronomy-inspired concept for designing multi-immersion microscope objectives with high numerical aperture, long working distance and large field of view. The Schmidt objective uses a spherical mirror and a correction plate to focus light. It is well

Research Briefing Published: 13 March 2023 Nature Biotechnology (2023)Cite this article 51 Accesses 2 Altmetric Metrics details Subjects Leveraging advances in hardware and probes, we have combined innovations in optics and algorithms to allow automated single-molecule-based super-resolution imaging at unprecedented throughput. This approach allows us to obtain nanoscale information from large cell populations, bridging the

Data availabilityAdditional (for example, raw image) data that support the findings of this study are available from the corresponding author. Because of their size, they can only be shared on reasonable request. Source data are provided with this paper.Code availabilityThe custom software or code generated during the current study is available from the corresponding author.