extending

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

MainOver the last 25 years, shotgun metagenomic sequencing1 and associated computational methods have developed as robust, efficient ways to study the taxonomic composition2,3,4,5,6 and functional potential4,7,8 of complex microbial communities populating human, animal and natural environments. Genome assembly methods developed for microbial isolates have been expanded to apply to shotgun metagenomes, but while they excel