Nature Biotechnology, Published online: 19 August 2025; doi:10.1038/s41587-025-02770-1A vast landscape of ‘undruggable’ cancer targets remains beyond the reach of conventional therapeutic agents. Recent advances in artificial intelligence (AI), however, are challenging this paradigm. Synthesizing insights from a Cancer Moonshot workshop, we argue that systemically addressing the undruggable target space with AI requires a new conceptual framework…
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Karen Akinsanya
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