{"id":889504,"date":"2026-02-02T02:12:09","date_gmt":"2026-02-02T08:12:09","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2026\/02\/02\/engineered-aldehyde-dehydrogenases-for-amide-bond-formation-science\/"},"modified":"2026-02-02T02:12:09","modified_gmt":"2026-02-02T08:12:09","slug":"engineered-aldehyde-dehydrogenases-for-amide-bond-formation-science","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2026\/02\/02\/engineered-aldehyde-dehydrogenases-for-amide-bond-formation-science\/","title":{"rendered":"Engineered aldehyde dehydrogenases for amide bond formation | Science"},"content":{"rendered":"<p>Science &#038; Nature Amide bond formation is widely used in pharmaceutical synthesis, typically involving stoichiometric coupling reagents to activate carboxylic acid substrates for a condensation reaction. As an alternative approach, we repurposed aldehyde dehydrogenases &#8230;<br \/><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adw3365\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a>Augustine Fleishman<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Science &#038; Nature Amide bond formation is widely used in pharmaceutical synthesis, typically involving stoichiometric coupling reagents to activate carboxylic acid substrates for a condensation reaction. As an alternative approach, we repurposed aldehyde dehydrogenases &#8230;Read MoreAugustine Fleishman<\/p>\n","protected":false},"author":1,"featured_media":889505,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[147865,30978,536],"tags":[],"class_list":["post-889504","post","type-post","status-publish","format-standard","has-post-thumbnail","category-aldehyde","category-engineered","category-science-nature"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/889504","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=889504"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/889504\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/889505"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=889504"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=889504"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=889504"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}