{"id":867728,"date":"2025-08-24T23:12:27","date_gmt":"2025-08-25T04:12:27","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2025\/08\/24\/load-and-lock-an-emerging-class-of-therapeutics-that-influence-macromolecular-dissociation-science\/"},"modified":"2025-08-24T23:12:27","modified_gmt":"2025-08-25T04:12:27","slug":"load-and-lock-an-emerging-class-of-therapeutics-that-influence-macromolecular-dissociation-science","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2025\/08\/24\/load-and-lock-an-emerging-class-of-therapeutics-that-influence-macromolecular-dissociation-science\/","title":{"rendered":"Load and lock: An emerging class of therapeutics that influence macromolecular dissociation | Science"},"content":{"rendered":"<p>Science &#038; Nature Biology is governed by macromolecular interactions, perturbation of which often lies at the heart of disease. Most therapeutic drugs, whether they are small molecules or biologics, exert their effects through impeding such interactions, whether they are &#8230;<br \/><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adx3595\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a>Rubi Geddes<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Science &#038; Nature Biology is governed by macromolecular interactions, perturbation of which often lies at the heart of disease. Most therapeutic drugs, whether they are small molecules or biologics, exert their effects through impeding such interactions, whether they are &#8230;Read MoreRubi Geddes<\/p>\n","protected":false},"author":1,"featured_media":867729,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4430,28756,536],"tags":[],"class_list":{"0":"post-867728","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-class","8":"category-emerging","9":"category-science-nature"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/867728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=867728"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/867728\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/867729"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=867728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=867728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=867728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}