{"id":863471,"date":"2025-07-19T00:13:17","date_gmt":"2025-07-19T05:13:17","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2025\/07\/19\/thyroid-surgery-complication-may-not-affect-quality-of-life\/"},"modified":"2025-07-19T00:13:17","modified_gmt":"2025-07-19T05:13:17","slug":"thyroid-surgery-complication-may-not-affect-quality-of-life","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2025\/07\/19\/thyroid-surgery-complication-may-not-affect-quality-of-life\/","title":{"rendered":"Thyroid Surgery Complication May Not Affect Quality of Life"},"content":{"rendered":"<div id=\"article-body_2025a1000b9m\">\n<h2><strong>TOPLINE:<\/strong><\/h2>\n<p>A population-based Swedish study showed no significant differences in health-related quality of life between patients with and without permanent <a href=\"https:\/\/emedicine.medscape.com\/article\/922204-overview\">hypoparathyroidism<\/a> after total <a href=\"https:\/\/emedicine.medscape.com\/article\/1891109-overview\">thyroidectomy<\/a> over a mean follow-up duration of 11 years.<\/p>\n<h2><strong>METHODOLOGY:<\/strong><\/h2>\n<ul>\n<li>Researchers in Sweden conducted a population-based retrospective cohort study to examine differences in health-related quality of life between patients with and without hypoparathyroidism who underwent total thyroidectomy for benign thyroid disease between 2005 and 2015.<\/li>\n<li>They analysed data of 46 patients (mean age, 35.8 years) with permanent hypoparathyroidism and 653 patients (mean age, 45.7 years) without the condition.<\/li>\n<li>Permanent hypoparathyroidism was defined as low serum levels of <a href=\"https:\/\/emedicine.medscape.com\/article\/2089334-overview\">parathyroid hormone<\/a> with hypocalcaemia at 12 months post-surgery or at least one failed attempt to manage levels of calcium and\/or active <a href=\"https:\/\/reference.medscape.com\/drug\/drisdol-calciferol-vitamind-344417\">vitamin D<\/a> at 12-24 months post-surgery.<\/li>\n<li>The quality of life was assessed using the Swedish version of the 36-item Short Form Health Survey questionnaire, evaluating eight health domains and two summary scores.<\/li>\n<li>The mean follow-up duration of the study was 10.9 years.<\/li>\n<\/ul>\n<h2><strong>TAKEAWAY:<\/strong><\/h2>\n<ul>\n<li>No significant differences in baseline characteristics, including indication for surgery, were observed between patients with and without permanent hypoparathyroidism; however, those with permanent hypoparathyroidism were significantly younger than those without (mean age, 35.8 vs 45.7 years; <em>P<\/em> < .001).<\/li>\n<li>Similarly, no significant differences were observed between patients with and without permanent hypoparathyroidism across all health domains and the summary component scores (<em>P<\/em> > .05 for all).<\/li>\n<li>A comparable proportion of patients with and without permanent hypoparathyroidism scored within or above the average range on the physical component summary (<em>P<\/em> = .802) and the mental component summary (<em>P<\/em> = .387).<\/li>\n<\/ul>\n<h2><strong>IN PRACTICE:<\/strong><\/h2>\n<p>&#8220;It is possible that the impact on HRQoL [health-related quality of life] is most prominent during the initial interval and diminishes over time as patients adapt to their life-long complication,&#8221; the authors wrote.<\/p>\n<h2><strong>SOURCE:<\/strong><\/h2>\n<p>This study was led by Matilda Anneb\u00e4ck, Uppsala University Hospital, Uppsala, Sweden. It was <a href=\"https:\/\/academic.oup.com\/bjsopen\/article\/9\/3\/zraf032\/8126390?login=false\" rel=\"nofollow\" target=\"_blank\">published online<\/a> on May 07, 2025, in <em>BJS Open<\/em>.<\/p>\n<h2><strong>LIMITATIONS:<\/strong><\/h2>\n<p>This study did not include data on socioeconomic status, comorbidities, and <a href=\"https:\/\/emedicine.medscape.com\/article\/2074091-overview\">thyroid-stimulating hormone<\/a> levels. The response rate of the study was 48.3%, which could have introduced a non-response bias. The 36-item Short Form Health Survey questionnaire might not fully capture aspects unique to hypoparathyroidism.<\/p>\n<h2><strong>DISCLOSURES:<\/strong><\/h2>\n<p>This study was supported by grants from the Bergholm Foundation. The authors declared having no conflicts of interest.<\/p>\n<p><em>This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.<\/em><\/p>\n<\/div>\n<p> Thomas Menjivar <br \/><a href=\"https:\/\/www.medscape.com\/viewarticle\/thyroid-surgery-complication-may-not-affect-quality-life-2025a1000b9m\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>TOPLINE: A population-based Swedish study showed no significant differences in health-related quality of life between patients with and without permanent hypoparathyroidism after total thyroidectomy over a mean follow-up duration of 11 years. METHODOLOGY: Researchers in Sweden conducted a population-based retrospective cohort study to examine differences in health-related quality of life between patients with and without<\/p>\n","protected":false},"author":1,"featured_media":863472,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4082,41224],"tags":[11097,145376],"class_list":{"0":"post-863471","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-surgery","8":"category-thyroid","9":"tag-surgery","10":"tag-thyroid"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/863471","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=863471"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/863471\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/863472"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=863471"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=863471"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=863471"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}