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Whether among passengers or crew, seasickness remains one of the most frequent medical issues encountered on board ships. At the 131st Congress<\/a> of the German Society for Internal Medicine, Andreas H. Leischker, MD, specialist in internal medicine, emergency medicine, aviation medicine, and sports medicine and an experienced ship physician, shared practical insights on the prevention and management of motion sickness at sea.<\/p>\n This article is based on Leischker\u2019s lecture delivered during the congress.<\/p>\n Approximately 25% of cruise passengers experience seasickness (motion sickness) within the first 3 days of travel \u2014 this figure can rise to 60% during rough seas, according to Leischker. \u201cSeasickness has a strong genetic component, and estrogen appears to play a role,\u201d he noted. In clinical practice, it is evident that women are more affected than men, with pregnant women particularly being vulnerable.<\/p>\n Children aged 6-12 years are also frequently affected, while children younger than 2 years are rarely affected. Individuals older than 50 years tend to be less affected due to age-related decline in vestibular system sensitivity.<\/p>\n Leischker explained that approximately 50% of people adapt well to sea conditions. This adaptation process usually takes 1-3 weeks, which exceeds the duration of most passenger cruises but is highly relevant for ship crew members. Once adaptation is achieved, it typically persists for up to 3 months after disembarkation. \u201cIf someone hasn\u2019t worked at sea for 3 months, they will need to readapt,\u201d he emphasized.<\/p>\n Seasickness results from sensory conflict among three systems: The visual system, the vestibular apparatus (inner ear), and proprioceptive input \u2014 especially from the feet. In rough conditions, these systems relay conflicting signals to the brain, triggering symptoms due to sensory mismatch.<\/p>\n Common symptoms include:<\/p>\n Less commonly occurring symptoms were headaches and bradycardia.<\/p>\n Leischker stressed the importance of conducting a thorough physical examination when passengers or crew members present with symptoms suggestive of seasickness. \u201cA patient complaining of vomiting or headache in rough seas may very well have seasickness, but more serious conditions \u2014 such as a subarachnoid hemorrhage \u2014 must always be ruled out,\u201d he cautioned.<\/p>\n When assessing patients with symptoms suggestive of seasickness \u2014 especially on board ships \u2014 it is important to rule out more serious conditions. According to Leischker, the following differential diagnoses should be kept in mind:<\/p>\n Behavioral modification can play a key role in preventing motion sickness. Because histamine pathways are implicated, Leischker advises avoiding histamine-rich foods (eg, aged cheese, cured meats, and fermented products) and alcohol.<\/p>\n Additional non-pharmacologic strategies include:<\/p>\n Scopolamine:<\/strong> Scopolamine has the most robust clinical evidence and the highest number of randomized controlled trials supporting its use in motion sickness prevention. The transdermal patch form is particularly well-studied and should be applied at least 8 hours before expected exposure to rough seas, which can generally be predicted using weather forecasts. The effect of the patch lasts up to 72 hours.<\/p>\n If the patch cannot be applied in advance, oral scopolamine (0.3-0.6 mg) may be used prophylactically, with administration approximately 1 hour before exposure. Combining oral and transdermal forms may improve efficacy. However, its use is contraindicated in patients with glaucoma or benign prostatic hyperplasia, and delirium may occur in patients with dementia.<\/p>\n Ginger:<\/strong> Clinical data also support the use of ginger as a prophylactic agent for motion sickness. Fresh ginger is generally more effective than dried preparations. In one study, fresh ginger outperformed 100 mg of dimenhydrinate in reducing symptoms. When used in a capsule form, a total dose of 940 mg (two capsules) was found to be effective.<\/p>\n Vitamin C:<\/strong> A study involving young military personnel younger than 27 years evaluated the prophylactic use of vitamin C for motion sickness. The results indicated a preventive effect but only at a high oral dose of 2 g, which may lead to gastrointestinal side effects, particularly diarrhea.<\/p>\n \u201cIf every passenger affected by seasickness sought medical attention, the onboard medical center would be overwhelmed,\u201d noted Leischker. To manage demand, the placebo effect is sometimes utilized: Homeopathic remedies are available at the ship\u2019s reception desk and are effective in approximately 40% of cases. \u201cWe typically only see those patients for whom this approach has not been sufficient,\u201d Leischker explained.<\/p>\n Acupuncture and acupressure \u2014 specifically stimulation of the Pericardium 6 (Nei Guan) point \u2014 have shown some effectiveness but are not practical on large cruise ships due to time and personnel constraints.<\/p>\n Dimenhydrinate is a frequently used treatment for nausea and dizziness. However, due to its sedative properties, it is not suitable for crew members. \u201cIn rough seas, the entire crew \u2014 whether it\u2019s the cook or a technician \u2014 must remain fully operational in case of emergency,\u201d emphasized Leischker.<\/p>\n Special care must be taken when dosing dimenhydrinate in children younger than 3 years, as overdosing can lead to seizures and respiratory depression.<\/p>\n Dimenhydrinate via suppositories:<\/strong> When using suppository formulations (eg, Vomex A), the following dosages apply:<\/p>\n The total maximum dosage should not exceed 5 mg\/kg\/24 hours.<\/p>\n Dimenhydrinate intravenously:<\/strong> Intravenous administration (62 mg in 10 mL) is also effective and fast-acting. Up to three ampoules per day can be given to adults. However, Leischker pointed out a practical limitation: \u201cIn a mass casualty scenario, our onboard facility with only four beds reaches capacity quickly. We therefore need an alternative for managing a high volume of cases\u201d \u2014 which is intramuscular administration.<\/p>\n Dimenhydrinate intramuscularly:<\/strong> Intramuscular delivery provides a higher depot dose and prolonged action. It is especially useful for patients who are already vomiting. An additional advantage is patient preference: \u201cMost adults dislike suppositories. From around age 14, nearly all prefer an injection,\u201d said Leischker.<\/p>\n While prescribing information typically recommends injecting the drug deep into the gluteal muscle, Leischker advises against this: \u201cDo not strictly follow that guidance. Two milliliters are well-tolerated in most upper arm muscles, and this avoids the risk of sciatic nerve injury.\u201d Contraindications for dimenhydrinate include narrow-angle glaucoma, prostatic hyperplasia, epilepsy, and Wolff-Parkinson-White syndrome.<\/p>\n Because dimenhydrinate\u2019s sedative effect is incompatible with operational duties, an off-label option is often used for crew members. Flunarizine, a calcium channel blocker taken orally in a tablet form, is effective without sedation. However, it is contraindicated in patients with Parkinson\u2019s disease or depression.<\/p>\n Prevention:<\/strong> Scopolamine patches and tablets are effective; ginger is a non-pharmacologic alternative.<\/p>\n Therapy:<\/strong> Intramuscular dimenhydrinate is effective for passengers; flunarizine is a practical option for crew.<\/p>\n This story was translated from <\/em>Coliquio<\/em><\/a>.<\/em><\/p>\n<\/div>\nBusiness Who Is Affected<\/strong><\/h2>\n
Business Adaptation to Sea Travel<\/strong><\/h2>\n
Business Pathophysiology and Symptoms<\/strong><\/h2>\n
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Business Importance of Differential Diagnosis<\/strong><\/h2>\n
Business Differential Diagnoses<\/strong><\/h2>\n
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Business Behavioral Prevention Strategies<\/strong><\/h2>\n
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Business Pharmacologic Prevention Options<\/strong><\/h2>\n
Business Therapy for Seasickness<\/strong><\/h2>\n
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Business Crew Treatment<\/strong><\/h2>\n
Business Take-Home Messages<\/strong><\/h2>\n