{"id":846859,"date":"2025-05-08T21:12:19","date_gmt":"2025-05-09T02:12:19","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2025\/05\/08\/scientists-warn-just-1-day-of-sleep-deprivation-can-disrupt-your-immune-system\/"},"modified":"2025-05-08T21:12:19","modified_gmt":"2025-05-09T02:12:19","slug":"scientists-warn-just-1-day-of-sleep-deprivation-can-disrupt-your-immune-system","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2025\/05\/08\/scientists-warn-just-1-day-of-sleep-deprivation-can-disrupt-your-immune-system\/","title":{"rendered":"Scientists Warn: Just 1 Day of Sleep Deprivation Can Disrupt Your Immune System"},"content":{"rendered":"<article id=\"post-458130\">\n<div>\n<figure id=\"attachment_258797\" aria-describedby=\"caption-attachment-258797\"><a href=\"https:\/\/scitechdaily.com\/images\/Cant-Sleep-Insomnia-Headache.jpg\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/scitechdaily.com\/images\/Cant-Sleep-Insomnia-Headache-777x406.jpg\" alt=\"Cant Sleep Insomnia Headache\" width=\"777\" height=\"406\"  ><\/a><figcaption id=\"caption-attachment-258797\">A study in The Journal of Immunology reveals that poor sleep quality can alter immune cell profiles, mimicking those seen in obesity-related inflammation. Researchers found that sleep deprivation in healthy individuals triggered immune changes linked to chronic diseases like diabetes and cardiovascular conditions. The study highlights the need for better sleep practices and future interventions to improve immune health and prevent inflammation-related illnesses.<\/figcaption><\/figure>\n<p><strong>Poor sleep quality alters immune function, increasing inflammation and disease risk. One night of sleep loss can mimic immune changes seen in obesity, stressing the importance of sleep for overall health.<\/strong><\/p>\n<p>New research highlights the significant impact of sleep quality on the immune system and its potential link to diseases such as obesity, diabetes, and cardiovascular conditions.<\/p>\n<p>A study published in <em>The Journal of Immunology<\/em> found that just one night of 24-hour sleep deprivation in young, healthy individuals altered their immune cell profile to resemble that of people with obesity\u2014a condition associated with chronic inflammation. This finding suggests that the immune system is highly responsive to sleep patterns and can adapt quickly to disruptions. Researchers caution that if these immune changes persist, they could contribute to long-term inflammation and an increased risk of disease.<\/p>\n<p>Substantial evidence exists linking sleep disorders and disturbances to an array of chronic conditions and morbidity, such as type 2 diabetes and cardiovascular diseases. It\u2019s also known that poor health outcomes can be driven by chronic inflammation but the direct influence of sleep on circulating immune cells, such as monocytes, is not as well understood.<\/p>\n<p>Monocytes are a vital component of the innate immune system \u2013 the body\u2019s first line of defense that rapidly detects pathogens and kickstarts the immune response. There are three subsets of monocytes \u2013 classical, intermediate, and non-classical monocytes. Non-classical monocytes patrol the body, sense and respond to inflammatory cues, and help to maintain and regulate the immune response.<\/p>\n<h4>Sleep, Inflammation, and Obesity<\/h4>\n<p>In this study, the researchers from the Dasman Diabetes Institute, Kuwait City, Kuwait, analyzed the sleep patterns of 237 healthy adult participants of varying <span aria-describedby=\"tt\" data-cmtooltip=\"\n\n<div class=glossaryItemTitle>BMI<\/div>\n<div class=glossaryItemBody>Body Mass Index (BMI) is a numerical value derived from an individual&#039;s weight and height, used to categorize body weight status. Calculated by dividing a person&#039;s weight in kilograms by the square of their height in meters (kg\/m\u00b2), BMI provides a quick assessment of whether an individual is underweight, normal weight, overweight, or obese. While widely used in health and fitness, BMI has limitations as it does not account for factors like muscle mass, bone density, or fat distribution, which can affect body composition.<\/div>\n<p>&#8221; data-gt-translate-attributes=&#8221;[{&#8220;attribute&#8221;:&#8221;data-cmtooltip&#8221;, &#8220;format&#8221;:&#8221;html&#8221;}]&#8221; tabindex=&#8221;0&#8243; role=&#8221;link&#8221;>BMI<\/span>, and took blood samples to profile the levels of different monocytes as well as markers of inflammation. They found that obese individuals had significantly lower sleep quality and higher chronic low-grade inflammation compared to the lean group. Non-classical monocytes were also increased significantly in obese participants, correlating with reduced sleep quality and elevated pro-inflammatory markers.<\/p>\n<p>Five, healthy lean individuals also took part in a 24-hour sleep deprivation part of the study and had blood samples collected throughout. The researchers found that sleep deprivation altered the profile of monocytes like what was seen in obese participants, supporting the role of sleep health in modulating inflammation.<\/p>\n<p>Dr Fatema Al-Rashed, who led the study, said: \u201cOur findings underscore a growing public health challenge. Advancements in technology, prolonged screen time, and shifting societal norms are increasingly disruptive to regular sleeping hours. This disruption in sleep has profound implications for immune health and overall well-being.\u201d<\/p>\n<p>The researchers next want to explore in greater detail the mechanisms linking sleep deprivation to immune changes. They also want to find out if interventions such as structured sleep therapies or technology-use guidelines can reverse these immune alterations.<\/p>\n<p>\u201cIn the long term, we aim for this research to drive policies and strategies that recognize the critical role of sleep in public health. We envision workplace reforms and educational campaigns promoting better sleep practices, particularly for populations at risk of sleep disruption due to technological and occupational demands. Ultimately, this could help mitigate the burden of inflammatory diseases like obesity, diabetes, and cardiovascular diseases,\u201d said Dr Al-Rashed.<\/p>\n<p>Reference: \u201cImpact of sleep deprivation on monocyte subclasses and function\u201d by Fatema Al-Rashed, Halemah Alsaeed, Nadeem Akhter, Haya Alabduljader, Fahd Al-Mulla and Rasheed Ahmad, 24 February 2025, <i>The Journal of Immunology<\/i>.<br \/>\n<a href=\"https:\/\/doi.org\/10.1093\/jimmun\/vkae016\" data-google-interstitial=\"false\">DOI: 10.1093\/jimmun\/vkae016<\/a><\/p>\n<\/p><\/div>\n<p>\t\t\t American Association of Immunologists <br \/><a href=\"https:\/\/scitechdaily.com\/scientists-warn-just-1-day-of-sleep-deprivation-can-disrupt-your-immune-system\/\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study in The Journal of Immunology reveals that poor sleep quality can alter immune cell profiles, mimicking those seen in obesity-related inflammation. Researchers found that sleep deprivation in healthy individuals triggered immune changes linked to chronic diseases like diabetes and cardiovascular conditions. The study highlights the need for better sleep practices and future interventions<\/p>\n","protected":false},"author":1,"featured_media":846860,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3807,1178],"tags":[10539,8815],"class_list":{"0":"post-846859","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-scientists","8":"category-sleep","9":"tag-scientists","10":"tag-sleep"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/846859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=846859"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/846859\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/846860"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=846859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=846859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=846859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}