{"id":843255,"date":"2025-04-24T13:12:41","date_gmt":"2025-04-24T18:12:41","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2025\/04\/24\/computational-design-of-serine-hydrolases-science\/"},"modified":"2025-04-24T13:12:41","modified_gmt":"2025-04-24T18:12:41","slug":"computational-design-of-serine-hydrolases-science","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2025\/04\/24\/computational-design-of-serine-hydrolases-science\/","title":{"rendered":"Computational design of serine hydrolases | Science"},"content":{"rendered":"<p>Science &#038; Nature The design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabilities of RFdiffusion with an ensemble generation method for &#8230;<br \/><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adu2454\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a>Camellia Serna<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Science &#038; Nature The design of enzymes with complex active sites that mediate multistep reactions remains an outstanding challenge. With serine hydrolases as a model system, we combined the generative capabilities of RFdiffusion with an ensemble generation method for &#8230;Read MoreCamellia Serna<\/p>\n","protected":false},"author":1,"featured_media":843256,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46592,2440,536],"tags":[],"class_list":{"0":"post-843255","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-computational","8":"category-design","9":"category-science-nature"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/843255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=843255"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/843255\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/843256"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=843255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=843255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=843255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}