{"id":810434,"date":"2024-12-06T10:13:40","date_gmt":"2024-12-06T16:13:40","guid":{"rendered":"https:\/\/newsycanuse.com\/index.php\/2024\/12\/06\/engineering-synthetic-suppressor-t-cells-that-execute-locally-targeted-immunoprotective-programs-science\/"},"modified":"2024-12-06T10:13:40","modified_gmt":"2024-12-06T16:13:40","slug":"engineering-synthetic-suppressor-t-cells-that-execute-locally-targeted-immunoprotective-programs-science","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2024\/12\/06\/engineering-synthetic-suppressor-t-cells-that-execute-locally-targeted-immunoprotective-programs-science\/","title":{"rendered":"Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs | Science"},"content":{"rendered":"<p>Science &#038; Nature Immune homeostasis requires a balance of inflammatory and suppressive activities. To design cells potentially useful for local immune suppression, we engineered conventional CD4+ T cells with synthetic Notch (synNotch) receptors driving antigen-triggered &#8230;<br \/><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adl4793\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a>Dion Grumbles<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Science &#038; Nature Immune homeostasis requires a balance of inflammatory and suppressive activities. To design cells potentially useful for local immune suppression, we engineered conventional CD4+ T cells with synthetic Notch (synNotch) receptors driving antigen-triggered &#8230;Read MoreDion Grumbles<\/p>\n","protected":false},"author":1,"featured_media":810435,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30555,536,33204],"tags":[],"class_list":{"0":"post-810434","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-engineering","8":"category-science-nature","9":"category-synthetic"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/810434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=810434"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/810434\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/810435"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=810434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=810434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=810434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}