{"id":606636,"date":"2023-02-10T13:49:37","date_gmt":"2023-02-10T19:49:37","guid":{"rendered":"https:\/\/news.sellorbuyhomefast.com\/index.php\/2023\/02\/10\/suboptimal-sleep-duration-linked-to-poor-brain-health\/"},"modified":"2023-02-10T13:49:37","modified_gmt":"2023-02-10T19:49:37","slug":"suboptimal-sleep-duration-linked-to-poor-brain-health","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2023\/02\/10\/suboptimal-sleep-duration-linked-to-poor-brain-health\/","title":{"rendered":"Suboptimal Sleep Duration Linked to Poor Brain Health"},"content":{"rendered":"<div>\n<nav>\n      <a href=\"http:\/\/www.medpagetoday.com\/meetingcoverage\" tabindex=\"15.1\" itemprop=\"articleSection\">Meeting Coverage<\/a><br \/>\n      <span>><\/span><br \/>\n      <a href=\"http:\/\/www.medpagetoday.com\/meetingcoverage\/isc\" tabindex=\"15.2\">ISC<\/a><br \/>\n  <\/nav>\n<h2>\u2014 Middle-age patients with worse sleep saw increased white matter hyperintensities on MRI<\/h2>\n<p>\n      by<br \/>\n             <a href=\"https:\/\/www.medpagetoday.com\/people\/es4983\/elizabeth-short\">Elizabeth Short<\/a>, Staff Writer, MedPage Today                        <span itemprop=\"datePublished\" content=\"February 9, 2023\"><br \/>\n        February 9, 2023<br \/>\n      <\/span>\n          <\/p>\n<\/div>\n<div id=\"js-main-content-region\" itemtype=\"http:\/\/schema.org\/articleBody\" itemid=\"#main-content-region\">\n<p>DALLAS  &#8212;  Optimal sleep duration was associated with better neuroimaging brain health profiles among middle-age adults without stroke, according to a cross-sectional study of U.K. Biobank participants.<\/p>\n<p>Compared with optimal sleep duration (7 to <9 hours per night), suboptimal sleep duration was significantly associated with higher white matter hyperintensity presence and volume (<em>P<\/em><0.001 for both) after adjusting for age, sex, and race\/ethnicity, reported Santiago Clocchiatti-Tuozzo, MD, of Yale School of Medicine in New Haven, Connecticut, during the American Stroke Association's <a href=\"https:\/\/www.medpagetoday.com\/meetingcoverage\/isc\" target=\"_blank\" rel=\"noopener\">International Stroke Conference<\/a>.<\/p>\n<p>Suboptimal sleep was also linked with a significantly worse fractional anisotropy score (<em>P<\/em><0.001), but not a mean diffusivity score (<em>P<\/em>=0.5).<\/p>\n<p>Looking at 48 neuroanatomical tracts, the left and right cerebral peduncles and the left and right superior cerebellar peduncles were the most affected areas of the brain, Clocchiatti-Tuozzo noted.<\/p>\n<p>&#8220;We were actually really interested when we saw the results,&#8221; he told <em>MedPage Today<\/em> during a Q&#038;A. &#8220;Because they were in the cerebral peduncles and superior cerebellar peduncles, there may be a lot of associations regarding the conglomeration of a lot of axes across the brain, that conglomerate in these pillars, basically, of white matter.&#8221;<\/p>\n<p>In two separate models adjusted for age, sex, and race\/ethnicity plus cardiovascular risk factors or history of myocardial infarction, results remained similar for the two groups.<\/p>\n<p>This study followed the <a href=\"https:\/\/www.medpagetoday.com\/cardiology\/prevention\/99510\" target=\"_blank\" rel=\"noopener\">2022 decision<\/a> by the American Heart Association to include sleep duration as part of their cardiovascular health checklist. Their &#8220;Life&#8217;s Essential 8&#8221; is an updated version of their &#8220;Life&#8217;s Simple 7,&#8221; which also includes blood pressure, cholesterol, blood glucose, smoking, exercise, diet, and body mass index (BMI).<\/p>\n<p>For this study, the researchers included 28,899 participants in the optimal sleep group (mean age 55, 46.7% men) and 10,860 participants in the suboptimal sleep group (<7 or >9 hours per night; mean age 55.3, 47.6% men). Across both groups, the majority were never smokers, and mean BMI was 26 to 27. Similar proportions of participants had hyperlipidemia, diabetes, hypertension, and myocardial infarction.<\/p>\n<p>Participants were categorized by sleep duration, with the &#8220;best&#8221; length of sleep at 7 to <9 hours, followed by 9 to <10 hours, 6 to <7 hours, 5 to <6 or \u226510 hours, 4 to <5 hours, and <4 hours.<\/p>\n<p>Due to the observational nature of the study, a direct causality between length of sleep and markers of brain injury cannot be determined, Clocchiatti-Tuozzo noted. He also pointed out that the study was lacking in racial and ethnic diversity, which is one aspect that should be addressed by further research.<\/p>\n<p>&#8220;Two things have to be taken into consideration. The first is validation across other populations, with more diversity in racial and ethnic groups,&#8221; he said. &#8220;And, of course, that future research is needed to understand if the modification of sleep duration during middle age can actually change, not subclinical, but clinical outcomes in older ages.&#8221;<\/p>\n<div>\n<ul>\n<li>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/clf1.medpagetoday.com\/media\/images\/author\/EShort_188.jpg\" alt=\"author['full_name']\" width=\"50\" height=\"50\" previous-src=\"https:\/\/clf1.medpagetoday.com\/media\/images\/author\/EShort_188.jpg\">\n                            <\/p>\n<p><a href=\"https:\/\/www.medpagetoday.com\/people\/es4983\/elizabeth-short\">Elizabeth Short<\/a> is a staff writer for MedPage Today. She often covers pulmonology and allergy &#038; immunology.   <a href=\"https:\/\/twitter.com\/Eliz_JShort\">Follow <span><\/span><\/a>  <\/p>\n<\/li>\n<\/ul><\/div>\n<div>\n<div>\n<p>Disclosures<\/p>\n<div>\n<p>The study was funded by the American Heart Association, the National Institute on Aging, and the Neurocritical Care Society Research Fellowship.<\/p>\n<p>Clocchiatti-Tuozzo reported no disclosures. Co-authors reported several relationships with industry.<\/p>\n<\/div><\/div>\n<div>\n<p>Primary Source<\/p>\n<p>International Stroke Conference<\/p>\n<p><a href=\"https:\/\/professional.heart.org\/en\/meetings\/international-stroke-conference\" title=\"Opens in a new tab or window\" target=\"_blank\" rel=\"noopener\">Source Reference: <\/a>Clocchiatti-Tuozzo S, et al &#8220;Sleep duration is associated with clinically silent brain injury in middle-aged persons without stroke&#8221; ISC 2023.<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p><a href=\"https:\/\/www.medpagetoday.com\/meetingcoverage\/isc\/103040\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><br \/>\n Diego Coby<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Meeting Coverage &gt; ISC \u2014 Middle-age patients with worse sleep saw increased white matter hyperintensities on MRI by Elizabeth Short, Staff Writer, MedPage Today February 9, 2023 DALLAS &#8212; Optimal sleep duration was associated with better neuroimaging brain health profiles among middle-age adults without stroke, according to a cross-sectional study of U.K. Biobank participants. Compared<\/p>\n","protected":false},"author":1,"featured_media":606637,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1178,119025],"tags":[],"class_list":{"0":"post-606636","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-sleep","8":"category-suboptimal"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/606636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=606636"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/606636\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/606637"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=606636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=606636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=606636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}