{"id":604579,"date":"2023-02-04T13:49:31","date_gmt":"2023-02-04T19:49:31","guid":{"rendered":"https:\/\/news.sellorbuyhomefast.com\/index.php\/2023\/02\/04\/three-wild-technologies-about-to-change-health-care\/"},"modified":"2023-02-04T13:49:31","modified_gmt":"2023-02-04T19:49:31","slug":"three-wild-technologies-about-to-change-health-care","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2023\/02\/04\/three-wild-technologies-about-to-change-health-care\/","title":{"rendered":"Three Wild Technologies About to Change Health Care"},"content":{"rendered":"
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Feb. 3, 2023 \u2013 When I was a child, I watched syndicated episodes of the original <\/span>Star Trek<\/span><\/i>. I was dazzled by the space travel, sure, but also the medical technology.\u00a0<\/span><\/p>\n

A handheld \u201c<\/span>tricorder<\/span><\/a>\u201d detected diseases, while an intramuscular injector (\u201c<\/span>hypospray<\/span><\/a>\u201d) could treat them. Sickbay \u201c<\/span>biobeds<\/span><\/a>\u201d came with real-time health monitors that looked futuristic at the time but seem primitive today.<\/span><\/p>\n

Such visions inspired a lot of us kids to pursue science. Little did we know the real-life advances many of us would see in our lifetimes.\u00a0<\/span><\/p>\n

Artificial intelligence helping to spot disease, robots performing surgery, even video calls between doctor and patient \u2014 all these once sounded fantastical but now happen in clinical care.<\/span><\/p>\n

Now, in the 23rd year of the 21st century, you might not believe what we\u2019ll be capable of next. Three especially wild examples are moving closer to clinical reality.\u00a0<\/span><\/p>\n

Human Hibernation<\/strong>\u00a0<\/span><\/p>\n

Captain America, Han Solo, and Star Trek villain Khan \u2013 all were preserved at low temperatures and then revived, waking up alive and well months, decades, or centuries later. These are fictional examples, to be sure, but the science they\u2019re rooted in is real.\u00a0<\/span><\/p>\n<\/section>\n

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Rare cases of accidental hypothermia prove that full recovery is possible even after the heart stops beating. The drop in body temperature\u00a0<\/span>slows metabolism<\/span><\/a> and reduces the need for oxygen, stalling brain damage for an hour or more. (In\u00a0<\/span>one extreme case<\/a>, a climber survived after almost 9 hours of efforts to revive him.)\u00a0<\/span><\/p>\n

Useful for a space traveler? Maybe not. But it\u2019s potentially huge for someone with life-threatening injuries from a car accident or a gunshot wound.\u00a0<\/span><\/p>\n

That\u2019s the thinking behind a breakthrough procedure that came after decades of research on pigs and dogs, now in a clinical trial. The idea: A person with massive blood loss whose heart has stopped is injected with an ice-cold fluid, cooling them from the inside, down to about 50<\/span> F<\/span>.\u00a0<\/span><\/p>\n

Doctors already induce more modest hypothermia to protect the brain and other organs after cardiac arrest and during surgery on the aortic arch (the main artery carrying blood from the heart).\u00a0<\/span><\/p>\n<\/section>\n<\/div>\n

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But this experimental procedure \u2013 called emergency preservation and resuscitation (EPR) \u2013 goes far beyond that, dramatically \u201cdecreasing the body<\/span>\u2019<\/span>s need for oxygen and blood flow,\u201d says\u00a0<\/span>Samuel Tisherman, MD, a trauma surgeon\u00a0<\/span>at the University of Maryland Medical Center and\u00a0<\/span>the trial\u2019s lead researcher<\/span>. This puts the patient in a state of suspended animation that \u201ccould buy time for surgeons to stop the bleeding and save more of these patients.\u201d<\/span><\/p>\n

The technique has been done on\u00a0at least\u00a0<\/span>six patients<\/span><\/a>, though none were reported to survive. The\u00a0trial is expected to include 20 people by the time it wraps up in December, according to the listing on the\u00a0<\/span>U.S. clinical trials database<\/span><\/a>. Though given the strict requirements for candidates (emergency trauma victims who are not likely to survive), one can\u2019t exactly rely on a set schedule.\u00a0<\/span><\/p>\n

Still, the technology is promising. Someday we may even use it to keep patients in suspended animation for months or years, experts predict, helping astronauts through decades-long spaceflights, or stalling death in sick patients awaiting a cure.\u00a0<\/span><\/p>\n<\/section>\n

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Artificial Womb<\/strong><\/span><\/p>\n

Another sci-fi classic: growing human babies outside the womb. Think the fetus fields from <\/span>The\u00a0Matrix<\/span><\/i>, or the frozen embryos in\u00a0<\/span>Alien: Covenant<\/span><\/i>.<\/span><\/p>\n

In\u00a01923, British biologist J.B.S. Haldane coined a term for that \u2013\u00a0<\/span>ectogenesis.<\/span><\/i> He predicted that 70% of pregnancies would take place, from fertilization to birth, in artificial wombs by 2074. That many seems unlikely, but the timeline is on track.\u00a0<\/span><\/p>\n

Developing an embryo outside the womb is already routine in\u00a0<\/span>in vitro\u00a0<\/span><\/i>fertilization. And technology enables preterm babies to survive through much of the second half of gestation. Normal human pregnancy is 40 weeks,\u00a0and\u00a0<\/span>the youngest preterm baby ever to survive was\u00a0<\/span>21 weeks and 1 day<\/span><\/a> old, just a few days younger than a smattering of others who lived.\u00a0<\/span><\/p>\n

The biggest obstacle for babies younger than that is lung viability. Mechanical ventilation can damage the lungs and lead to a chronic (sometimes fatal) lung disease known as bronchopulmonary dysplasia. Avoiding this would mean figuring out a way to maintain fetal circulation \u2013 the intricate system that delivers oxygenated blood from the placenta to the fetus via the umbilical cord. Researchers at Children\u2019s Hospital of Philadelphia (CHOP) have done this using a fetal lamb.<\/span><\/p>\n<\/section>\n<\/div>\n

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The key to their invention is a substitute placenta: an oxygenator connected to the lamb\u2019s umbilical cord. Tubes inserted through the umbilical vein and arteries carry oxygenated blood from the \u201cplacenta\u201d to the fetus, and deoxygenated blood back out. The lamb resides in an artificial, fluid-filled amniotic sac until its lungs and other organs are developed.<\/span><\/p>\n

Fertility treatment could benefit, too.\u00a0“An artificial womb may substitute in situations in which a gestational carrier \u2013 surrogate \u2013 is indicated,\u201d says\u00a0<\/span>Paula Amato<\/span>, MD, a professor of obstetrics and gynecology at Oregon Health and Science University. (Amato is not involved in the CHOP research.) For example: when the mother is missing a uterus or can\u2019t carry a pregnancy safely.<\/span><\/p>\n

No date is set for clinical trials yet. But according to the\u00a0<\/span>research<\/span><\/a>, the main difference between human and lamb may come down to size. A lamb\u2019s umbilical vessels are larger, so feeding in a tube is easier. With today\u2019s advances in miniaturizing surgical methods, that seems like a challenge scientists can overcome.<\/span><\/p>\n<\/section>\n

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Messenger RNA Therapeutics<\/strong>\u00a0<\/span><\/p>\n

Back to\u00a0<\/span>Star Trek<\/span><\/i>. The hypospray injector\u2019s contents could cure just about any disease, even one newly discovered on a strange planet. That\u2019s not unlike messenger RNA (mRNA) technology, a breakthrough that enabled scientists to quickly develop some of the first COVID-19 vaccines.\u00a0<\/span><\/p>\n

But vaccines are just the beginning of what this technology can do.\u00a0<\/span><\/p>\n

A whole field of immunotherapy is emerging that uses mRNA to deliver instructions to produce chimeric antigen receptor-modified immune cells (CAR-modified immune cells). These cells are engineered to target diseased cells and tissues, like\u00a0<\/span>cancer cells<\/span><\/a> and harmful fibroblasts (scar tissue) that promote fibrosis in, for example, the\u00a0<\/span>heart<\/span><\/a> and lungs.\u00a0<\/span><\/p>\n

The field is bursting with rodent research, and clinical trials have started for treating some advanced-stage malignancies.<\/span><\/p>\n

Actual clinical use may be years away, but if all goes well, these medicines could help treat or even cure the core medical problems facing humanity. We\u2019re talking cancer, heart disease, neurodegenerative disease \u2013 transforming one therapy into another by simply changing the mRNA\u2019s \u201cnucleotide sequence,\u201d the blueprint containing instructions telling it what to do, and what disease to attack.\u00a0<\/span><\/p>\n

As this technology matures, we may start to feel as if we\u2019re really on\u00a0<\/span>Star Trek<\/span><\/i>, where Dr. Leonard \u201cBones\u201d McCoy pulls out the same device to treat just about every disease or injury.<\/span><\/p>\n<\/section>\n<\/div>\n<\/div>\n

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Read More<\/a>
\n Margarete Serna<\/p>\n","protected":false},"excerpt":{"rendered":"

Feb. 3, 2023 \u2013 When I was a child, I watched syndicated episodes of the original Star Trek. I was dazzled by the space travel, sure, but also the medical technology.\u00a0A handheld \u201ctricorder\u201d detected diseases, while an intramuscular injector (\u201chypospray\u201d) could treat them. Sickbay \u201cbiobeds\u201d came with real-time health monitors that looked futuristic at the<\/p>\n","protected":false},"author":1,"featured_media":604580,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41160,1862],"tags":[],"class_list":{"0":"post-604579","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-technologies","8":"category-three"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/604579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=604579"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/604579\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/604580"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=604579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=604579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=604579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}