{"id":595107,"date":"2023-01-07T07:53:33","date_gmt":"2023-01-07T13:53:33","guid":{"rendered":"https:\/\/news.sellorbuyhomefast.com\/index.php\/2023\/01\/07\/single-cell-recording-of-cellular-rnas-in-bacteria\/"},"modified":"2023-01-07T07:53:33","modified_gmt":"2023-01-07T13:53:33","slug":"single-cell-recording-of-cellular-rnas-in-bacteria","status":"publish","type":"post","link":"https:\/\/newsycanuse.com\/index.php\/2023\/01\/07\/single-cell-recording-of-cellular-rnas-in-bacteria\/","title":{"rendered":"Single-cell recording of cellular RNAs in bacteria"},"content":{"rendered":"<div>\n<header>\n<ul data-test=\"article-identifier\">\n<li data-test=\"article-category\">Research Briefing<\/li>\n<li><a href=\"http:\/\/www.nature.com\/#article-info\" data-track=\"click\" data-track-action=\"publication date\" data-track-label=\"link\">Published: <time datetime=\"2023-01-05\">05 January 2023<\/time><\/a><\/li>\n<\/ul>\n<ul data-test=\"authors-list\" data-component-authors-activator=\"authors-list\"><\/ul>\n<p data-container-section=\"info\">\n<p>    <a data-test=\"journal-link\" href=\"http:\/\/www.nature.com\/nbt\"><i data-test=\"journal-title\">Nature Biotechnology<\/i><\/a><\/p>\n<p>                         (<span data-test=\"article-publication-year\">2023<\/span>)<a href=\"http:\/\/www.nature.com\/#citeas\" data-track=\"click\" data-track-action=\"cite this article\" data-track-label=\"link\">Cite this article<\/a>\n                    <\/p>\n<div>\n<ul>\n<li>\n<p>97 <span>Accesses<\/span><\/p>\n<\/li>\n<li>\n<p>1 <span>Altmetric<\/span><\/p>\n<\/li>\n<li>\n<p><a href=\"http:\/\/www.nature.com\/articles\/s41587-022-01625-3\/metrics\" data-track=\"click\" data-track-action=\"view metrics\" data-track-label=\"link\" rel=\"nofollow\">Metrics <span>details<\/span><\/a><\/p>\n<\/li>\n<\/ul><\/div>\n<\/header>\n<div data-component=\"article-subject-links\">\n<h3>Subjects<\/h3>\n<\/p><\/div>\n<\/p><\/div>\n<div>\n<p>The collection of RNAs in a cell reflects its identity and behavior. Although probing these RNAs in the present is commonplace, peering into the past remains challenging. We developed TIGER (transcribed RNAs inferred by genetically encoded records) to record selected RNAs at the single-cell level, enabling us to connect the past with the present.<\/p>\n<div>\n<p>This is a preview of subscription content, <a href=\"https:\/\/wayf.springernature.com?redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41587-022-01625-3\" data-track=\"click\" data-track-action=\"institution access preview subscription\" data-track-label=\"link\">access via your institution<\/a><\/p>\n<\/p><\/div>\n<h2 id=\"access-options\">Access options<\/h2>\n<section>\n<div>\n<p>Subscribe to Nature+<\/p>\n<p>Get immediate online access to Nature and 55 other Nature journal<\/p>\n<\/div>\n<div>\n<p>Subscribe to Journal<\/p>\n<p>Get full journal access for 1 year<\/p>\n<div>\n<p id=\"subscription-price\">$99.00<\/p>\n<p>only $8.25 per issue<\/p>\n<\/div>\n<p>All prices are NET prices.<br \/> VAT will be added later in the checkout.<br \/>Tax calculation will be finalised during checkout.<\/p>\n<\/div>\n<div>\n<p>Buy article<\/p>\n<p>Get time limited or full article access on ReadCube.<\/p>\n<p id=\"readcube-price\">$32.00<\/p>\n<p>All prices are NET prices.<\/p>\n<\/div>\n<\/section>\n<nav>\n<h3>Additional access options:<\/h3>\n<ul>\n<li>\n            <a href=\"https:\/\/idp.nature.com\/authorize\/natureuser?client_id=grover&#038;redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41587-022-01625-3\" data-track=\"click\" data-track-action=\"login\" data-track-category=\"article body\" data-track-label=\"link\">Log in<\/a>\n        <\/li>\n<li>\n            <a href=\"https:\/\/www.springernature.com\/gp\/librarians\/licensing\/license-options\" data-track=\"click\" data-track-action=\"learn-subscription\" data-track-category=\"article body\" data-track-label=\"link\">Learn about institutional subscriptions<\/a>\n        <\/li>\n<\/ul>\n<\/nav>\n<div data-test=\"figure\" data-container-section=\"figure\" id=\"figure-1\">\n<figure><figcaption><b id=\"Fig1\" data-test=\"figure-caption-text\">Fig. 1: RNA recording in bacteria with TIGER.<\/b><\/figcaption><div><picture><source type=\"image\/webp\" ><img decoding=\"async\" src=\"http:\/\/media.springernature.com\/m312\/springer-static\/image\/art%3A10.1038%2Fs41587-022-01625-3\/MediaObjects\/41587_2022_1625_Fig1_HTML.png\" alt loading=\"lazy\" width=\"312\" height=\"151\"><\/picture><\/div>\n<\/figure>\n<\/div>\n<div>\n<div id=\"MagazineFulltextArticleBodySuffix\" aria-labelledby=\"Bib1\" data-title=\"References\">\n<h2 id=\"Bib1\">References<\/h2>\n<div data-container-section=\"references\" id=\"Bib1-content\">\n<ol data-track-component=\"outbound reference\">\n<li data-counter=\"1.\">\n<p id=\"ref-CR1\">Sheth, R. 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RNA recording in single bacterial cells using reprogrammed tracrRNAs. <i>Nat. Biotechnol<\/i>. <a href=\"https:\/\/doi.org\/10.1038\/s41587-022-01604-8\">https:\/\/doi.org\/10.1038\/s41587-022-01604-8<\/a> (2023).<\/p>\n<\/div>\n<\/div>\n<div id=\"rightslink-section\" data-title=\"Rights and permissions\">\n<h2 id=\"rightslink\">Rights and permissions<\/h2>\n<\/div>\n<div id=\"article-info-section\" aria-labelledby=\"article-info\" data-title=\"About this article\">\n<h2 id=\"article-info\">About this article<\/h2>\n<div id=\"article-info-content\">\n<p><a data-crossmark=\"10.1038\/s41587-022-01625-3\" target=\"_blank\" rel=\"noopener\" href=\"https:\/\/crossmark.crossref.org\/dialog\/?doi=10.1038\/s41587-022-01625-3\" data-track=\"click\" data-track-action=\"Click Crossmark\" data-track-label=\"link\" data-test=\"crossmark\"><img loading=\"lazy\" decoding=\"async\" width=\"57\" height=\"81\" alt=\"Verify currency and authenticity via CrossMark\" src=\"data:image\/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" 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1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>\"><\/a><\/p>\n<div>\n<h3 id=\"citeas\">Cite this article<\/h3>\n<p> Single-cell recording of cellular RNAs in bacteria.<br \/>\n                    <i>Nat Biotechnol<\/i>  (2023). https:\/\/doi.org\/10.1038\/s41587-022-01625-3<\/p>\n<p><a data-test=\"citation-link\" data-track=\"click\" data-track-action=\"download article citation\" data-track-label=\"link\" data-track-external rel=\"nofollow\" href=\"https:\/\/citation-needed.springer.com\/v2\/references\/10.1038\/s41587-022-01625-3?format=refman&#038;flavour=citation\">Download citation<\/a><\/p>\n<ul data-test=\"publication-history\">\n<li>\n<p>Published<span>: <\/span><span><time datetime=\"2023-01-05\">05 January 2023<\/time><\/span><\/p>\n<\/li>\n<li>\n<p><abbr title=\"Digital Object Identifier\">DOI<\/abbr><span>: <\/span><span>https:\/\/doi.org\/10.1038\/s41587-022-01625-3<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/p><\/div>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41587-022-01625-3\" class=\"button purchase\" rel=\"nofollow noopener\" target=\"_blank\">Read More<\/a><br \/>\n Becki Antes<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research Briefing Published: 05 January 2023 Nature Biotechnology (2023)Cite this article 97 Accesses 1 Altmetric Metrics details Subjects The collection of RNAs in a cell reflects its identity and behavior. Although probing these RNAs in the present is commonplace, peering into the past remains challenging. We developed TIGER (transcribed RNAs inferred by genetically encoded records)<\/p>\n","protected":false},"author":1,"featured_media":595108,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30055,536,30219],"tags":[],"class_list":{"0":"post-595107","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-recording","8":"category-science-nature","9":"category-single-cell"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/595107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/comments?post=595107"}],"version-history":[{"count":0,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/posts\/595107\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media\/595108"}],"wp:attachment":[{"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/media?parent=595107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/categories?post=595107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newsycanuse.com\/index.php\/wp-json\/wp\/v2\/tags?post=595107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}