Toes regrow with the help of cells at the base of the nail

  • RESEARCH HIGHLIGHT

Cells at the base of the nail are key to regeneration of missing digit tips.


Black and white image of an uninjured digit tip section

Tissue at the base of a mouse’s toe nail can develop into growth cells. Credit: N. Mahmud et al./Cell Rep.

Mice whose toe tips have been removed regrow them with the help of signature genes in cells in the base of the nail1.

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Nature 613, 219 (2023)

doi: https://doi.org/10.1038/d41586-022-04497-4

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