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49ers vs. Colts: Monday Night Football

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Discuss MNF with us here!

Week 16 of the 2025 NFL season ends tonight with a Monday Night Football game between the San Francisco 49ers and Indianapolis Colts.

The Philadelphia Eagles’ chances of getting the No. 1 seed are incredibly slim (like, 0.1% chance slim) but the Birds will remain mathematically alive for a first-round bye if the 49ers lose this game.

So, go Colts!

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